Mapping the gut microecological multi-omics signatures to
serum metabolome and their impact on cardiometabolic
health in elderly adults
Chu-wen Ling,a,d,e Kui Deng,a,b,e Yingdi Yang,a,e Hong-rou Lin,a,e Chun-ying Liu,a Bang-yan Li,a Wei Hu,a Xinxiu Liang,b Hui Zhao,b
Xin-yi Tang,c,f ,∗∗∗ Ju-Sheng Zheng,b,f ,∗∗ and Yu-ming Chena,f ,∗
aDepartment of Epidemiology, Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health,
Sun Yat-sen University, Guangzhou, 510080, China
bZhejiang Key Laboratory of Multi-Omics in Infection and Immunity, Center for Infectious Disease Research, School of Medicine,
Westlake University, Hangzhou, 310030, China
cDepartment of Pediatrics, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China
dDepartment of Clinical Nutrition, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences),
Southern Medical University, Guangzhou, 510080, China
Summary
Background Mapping gut microecological features to serum metabolites (SMs) will help identify functional links
between gut microbiome and cardiometabolic health.
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