Carnitine / Acylcarnitines screening is the most important part of the clinical diagnosis of amino acid, fatty acid or organic acid metabolism. Carnitine / Acylcarnitines screening allows to the diagnosis of over 30 metabolic diseases from a drop of blood samples taken with a screening card. This screening test occurred by measurement of Carnitine / Acylcarnitins with isotope dilution tandem mass spectrometry. LC-MS/MS is a powerful tool for gives results Carnitine / Acylcarnitines in 1.5 minutes.

Screening of following analytes can be performed by Zivak Carnitine / Acylcarnitine LC- MS/MS Analysis Kit and Zivak NeoZin Screening software. Main methods and procedures that have been selected are based on EN ISO 14971.

By the quantitative analysis of carnitine esters including such as free carnitine, C0, C2, C4, C6, C8, C10, C12, C14, C16, C16 OH, C18 , C18 OH carnitine disorders which are related with fatty acid oxidation.

By the quantitative analysis of carnitine esters including such as C3, C3DC, C4OH, C5, C5OH,C5DC carnitine, disorders which are related with organic acid metabolism.