CE-IVD certified and suitable for any kind of LC-MS/MS instrument
Zivak Neurotransmitters LC-MS/MS Analysis Kit was developed for accurate and sensitive analysis of Epinephrine, Norepinephrine , Dopamine ,Serotonin, Gamma-aminobutyric acid, Glutamate, Histamine, 5-Hydroxy-L-Tryptophan in urine samples. This validated analysis kit can be adapted to any LC-MS/MS system. Automation with Zivak Multitasker can be possible.
Neurotransmitters LC-MS/MS analysis kit in human urine sample
Neurotransmitters are endogenous chemicals that transmit signals from a neuron to a target cell across a synapse. Release of neurotransmitters usually follows arrival of an action potential at the synapse, but may also follow graded electrical potentials. Neurotransmitters are synthesized from plentiful and simple precursors, such as amino acids, which are readily available from the diet and which require only a small number of biosynthetic steps to convert. Because of their importance in metabolic processes, the analysis of neurotransmitters continues to be an area of importance in chromatography. A variety of modes of HPLC can be used to retain and separate these compounds. Detection in most analyses is a significant issue since typical optical techniques have low sensitivity. Since the presence of amine groups, electrochemical methods are often used. Mass spectroscopy is now becoming the method of choice because it provides high sensitivity and identification of the analytes.
Zivak Neurotransmitters LC-MS/MS Analysis Kit was developed for accurate analysis of neurotransmitters in urine samples.
Main methods and procedures that is selected by Zivak are based on EN ISO 13485 and 98/79/EC.