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Immunosuppressants LC-MS/MS analysis kit

Immunosuppressants LC-MS/MS analysis kit
CE-IVD certified and suitable for any kind of LC-MS/MS instrument
 

The Zivak Immunosuppressants (cyclosporine, everolimus, sirolimus and tacrolimus) LC-MS/MS  analysis kit can be used in combination with the Zivak-Multitasker as well as manually. Analysis run time for the manual version is 2 minutes. Due to the efficient and quite smart procedure of the Zivak-Multitasker, the automated version guarantees to receive results in just 2 minutes per test, including sample preparation-, sample injection- and analysis run time. Additionally, high accuracy is being rectified through external quality tests.

 
 

Quantitative LC-MS/MS analysis kit for Immunosuppressants including Sirolimus, Tacrolimus, Everolimus, Cyclosporin A in human whole blood samples.

Immunosuppressants are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to prevent the rejection of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver) and treat autoimmune diseases or diseases that are most likely of autoimmune origin (e.g., rheumatoid arthritis, multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, sarcoidosis, focal segmental glomerulosclerosis, Crohn's disease, Behcet's Disease, pemphigus, and ulcerative colitis). Immunosuppressants also can be used to treat some other non-autoimmune inflammatory diseases (e.g., long term allergic asthma control).

Most of the Immunosuppressants require monitoring blood concentrations, is called as therapeutic drug monitoring (TDM), for dosage adjustment. The measurement of low drug concentrations seen in biological fluids during drug treatment became possible by adopting new analytical technology. LC-MS/MS is a powerful tool for the measurement of the blood concentrations of the immunosupressants.

Zivak Immunosuppressants LC-MS/MS Analysis Kit was developed for quantitative monitoring of four immunosuppressants including Sirolimus, Tacrolimus, Everolimus and Cyclosporine in human whole blood samples and gives results in 2 minutes with minimal sample preparation. Main methods and procedures that have been selected are based on on EN ISO 13485 and 98/79/EC.

Immunosuppressants LC-MS/MS analysis kit 0
Immunosuppressants LC-MS/MS analysis kit 0 Immunosuppressants LC-MS/MS analysis kit 1

 

Immunosuppressants LC-MS/MS analysis kit 0 Immunosuppressants LC-MS/MS analysis kit 1
Immunosuppressants LC-MS/MS analysis kit 0
 
 
Immunosuppressants LC-MS/MS analysis kit 0 Immunosuppressants LC-MS/MS analysis kit 1

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